Donor Specific Antibody Grant Round 2018-2019-Open

CLDF- Donor Specific Antibodies-bespoke grant call 2018-19

Understanding the mechanisms of rejection is critical to improving the care of paediatric liver transplant recipients.  An emerging concept in allograft rejection is the presence of donor specific anti-HLA antibodies.  These have been associated with graft failure and rejection. Clinical studies in this area have been inconclusive, due to diverse methodologies and inadequate sample sizes.  The scientific committee of the CLDF have recognised this as an important area of research.  However, it is clear that in order to achieve this goal in a timely fashion requires collection of substantial numbers of patients through a coordinated and collaborative approach.

In order to facilitate this important area of research CLDF are delighted to announce that £20,000 is available to address the topic of donor specific anti-HLA antibodies.  Applications for this funding stream are now welcome.  Priority for funding will be given to innovative, well-powered and multi-centre research projects.

Successful applicants must agree to provide an interim progress and final project report, submit the findings for a poster or presentation at a CLDF event and aim to publish the findings if appropriate.

Proposals must be submitted to Alison Taylor at ceo@childliverdisease.org by the deadline of 9am on Monday 4th March 2019. Proposals submitted after this deadline will not be considered.

Proposals will be reviewed by CLDF’s Scientific Committee We aim to inform applicants of the outcome of their application during the mid April 2019.

Click here to download an application form: CLDF Research Grant Application Form DSA 2018-2019

Please contact Alison Taylor CEO at Children’s Liver Disease Foundation on ceo@childliverdisease.org if you would like to discuss any aspect of your proposal.