Title: Liver transplantation for pediatric genetic and metabolic disorders
Source: Liver Transplantation 2024, Aug 23. [E–publication]
Date of publication: August 2024
Publication type: Review article
Abstract: Pediatric genetic and metabolic liver diseases comprise a broad spectrum of conditions and represent the second most common indication for liver transplantation following biliary atresia. The decision to transplant can be challenging and requires consideration of several factors including hepatic involvement, extra-hepatic manifestations, and anticipated post-transplant outcomes. This review examines pediatric genetic and metabolic liver diseases, their pathophysiology, clinical presentation, and the role of liver transplantation.
